Detalhe da pesquisa
1.
Preclinical Characterization of Immunogenicity and Efficacy against Diarrhea from MecVax, a Multivalent Enterotoxigenic E. coli Vaccine Candidate.
Infect Immun
; 89(7): e0010621, 2021 06 16.
Artigo
Inglês
| MEDLINE | ID: mdl-33875477
2.
Enterotoxigenic Escherichia coli Adhesin-Toxoid Multiepitope Fusion Antigen CFA/I/II/IV-3xSTaN12S-mnLTG192G/L211A-Derived Antibodies Inhibit Adherence of Seven Adhesins, Neutralize Enterotoxicity of LT and STa Toxins, and Protect Piglets against Diarrhea.
Infect Immun
; 86(3)2018 03.
Artigo
Inglês
| MEDLINE | ID: mdl-29263112
3.
Characterization of heat-stable (STa) toxoids of enterotoxigenic Escherichia coli fused to double mutant heat-labile toxin peptide in inducing neutralizing Anti-STa antibodies.
Infect Immun
; 82(5): 1823-32, 2014 May.
Artigo
Inglês
| MEDLINE | ID: mdl-24549325
4.
Flagella from F18+Escherichia coli play a role in adhesion to pig epithelial cell lines.
Microb Pathog
; 55: 32-8, 2013 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-23046699
5.
Heat-labile- and heat-stable-toxoid fusions (LTR192G-STaP13F) of human enterotoxigenic Escherichia coli elicit neutralizing antitoxin antibodies.
Infect Immun
; 79(10): 4002-9, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21788385
6.
Antibodies derived from a toxoid MEFA (multiepitope fusion antigen) show neutralizing activities against heat-labile toxin (LT), heat-stable toxins (STa, STb), and Shiga toxin 2e (Stx2e) of porcine enterotoxigenic Escherichia coli (ETEC).
Vet Microbiol
; 202: 79-89, 2017 Apr.
Artigo
Inglês
| MEDLINE | ID: mdl-26878972
7.
Enterotoxigenic Escherichia coli heat-stable toxin and heat-labile toxin toxoid fusion 3xSTaN12S-dmLT induces neutralizing anti-STa antibodies in subcutaneously immunized mice.
FEMS Microbiol Lett
; 363(21)2016 Nov 01.
Artigo
Inglês
| MEDLINE | ID: mdl-27810884
8.
Antibodies derived from an enterotoxigenic Escherichia coli (ETEC) adhesin tip MEFA (multiepitope fusion antigen) against adherence of nine ETEC adhesins: CFA/I, CS1, CS2, CS3, CS4, CS5, CS6, CS21 and EtpA.
Vaccine
; 34(31): 3620-5, 2016 06 30.
Artigo
Inglês
| MEDLINE | ID: mdl-27228947
9.
Genetic fusions of a CFA/I/II/IV MEFA (multiepitope fusion antigen) and a toxoid fusion of heat-stable toxin (STa) and heat-labile toxin (LT) of enterotoxigenic Escherichia coli (ETEC) retain broad anti-CFA and antitoxin antigenicity.
PLoS One
; 10(3): e0121623, 2015.
Artigo
Inglês
| MEDLINE | ID: mdl-25803825
10.
Multiepitope fusion antigen induces broadly protective antibodies that prevent adherence of Escherichia coli strains expressing colonization factor antigen I (CFA/I), CFA/II, and CFA/IV.
Clin Vaccine Immunol
; 21(2): 243-9, 2014 Feb.
Artigo
Inglês
| MEDLINE | ID: mdl-24351757
11.
Oral immunization of a live attenuated Escherichia coli strain expressing a holotoxin-structured adhesin-toxoid fusion (1FaeG-FedF-LTA2:5LTB) protected young pigs against enterotoxigenic E. coli (ETEC) infection.
Vaccine
; 31(11): 1458-63, 2013 Mar 01.
Artigo
Inglês
| MEDLINE | ID: mdl-23375979
12.
Erratum to "Antibodies derived from a toxoid MEFA (multiepitope fusion antigen) show neutralizing activities against heat-labile toxin (LT), heat-stable toxins (STa, STb), and Shiga toxin 2e (Stx2e) of porcine enterotoxigenic Escherichia coli (ETEC)" [Vet. Microbiol. 202 (2017) 79-89].
Vet Microbiol
; 220: 114-115, 2018 07.
Artigo
Inglês
| MEDLINE | ID: mdl-29784499
13.
A multiepitope fusion antigen elicits neutralizing antibodies against enterotoxigenic Escherichia coli and homologous bovine viral diarrhea virus in vitro.
Clin Vaccine Immunol
; 20(7): 1076-83, 2013 Jul.
Artigo
Inglês
| MEDLINE | ID: mdl-23697572
14.
Escherichia coli expressing EAST1 toxin did not cause an increase of cAMP or cGMP levels in cells, and no diarrhea in 5-day old gnotobiotic pigs.
PLoS One
; 7(8): e43203, 2012.
Artigo
Inglês
| MEDLINE | ID: mdl-22905235
15.
The flagella of F18ab Escherichia coli is a virulence factor that contributes to infection in a IPEC-J2 cell model in vitro.
Vet Microbiol
; 160(1-2): 132-40, 2012 Nov 09.
Artigo
Inglês
| MEDLINE | ID: mdl-22658629
16.
A tripartite fusion, FaeG-FedF-LT(192)A2:B, of enterotoxigenic Escherichia coli (ETEC) elicits antibodies that neutralize cholera toxin, inhibit adherence of K88 (F4) and F18 fimbriae, and protect pigs against K88ac/heat-labile toxin infection.
Clin Vaccine Immunol
; 18(10): 1593-9, 2011 Oct.
Artigo
Inglês
| MEDLINE | ID: mdl-21813665